Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep583 | Endocrine-Related Cancer | ECE2022

Novel peptides and cell lines to expand the tools and models to study the potential of the somatostatin system in NETs

Mangili Federica , Moreno Montilla Maria Trinidad , Salamanca Jimenez Pilar , Garcia Vioque Victor , Encinas Rey Ricardo Blazquez , Alors-Perez Emilia , Mantovani Giovanna , Peverelli Erika , Schrader Jo rg , Ibanez Costa Alejandro , Castano Justo P.

Neuroendocrine tumors (NETs) represent a heterogeneous group of malignancies with increasing incidence worldwide, due in part to enhanced awareness and diagnosis improvements. Surgery is often effective for local disease, whereas disseminated or metastatic disease require pharmacological treatment, which is not always successful. Pancreatic (Pan-NETs) and pulmonary (Lung-NETs) neuroendocrine tumors frequently express somatostatin receptors (SSTs), providing the target for trea...